American Heart Association — Achieving the American Heart Association’s definition of ideal cardiovascular health may also help prevent chronic kidney disease, according to new research in the Journal of the American Heart Association.
Life’s Simple 7 are the ideal cardiovascular health factors/goals that include healthy blood pressure, cholesterol, blood sugar, diet, body weight, enough physical activity and not smoking.
“This study was the first to show that for people who are generally healthy, a higher number of ideal Life’s Simple 7 health factors is associated with a reduced risk of new-onset kidney disease,” said study author Casey M. Rebholz, Ph.D., M.P.H., M.S., assistant professor of epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
The study included 14,832 adults, aged 45-64. The researchers categorized the adults in each of Life’s Simple 7 measures as poor, intermediate or ideal. Participants were followed for an average of 22 years for the development of chronic kidney disease, a sometimes life-threatening condition where the kidneys are damaged and can’t filter waste from the body.
-Participants with the most Simple 7 health factors had the lowest risk of developing chronic kidney disease.
-About a third of study participants who had no ideal health factors at the study’s start developed chronic kidney disease during follow-up.
-Only 6.5 percent of participants with six or seven ideal health factors developed chronic kidney disease.
-Smoking, body mass index, physical activity, blood pressure and blood glucose were associated with chronic kidney disease risk, but diet and blood cholesterol were not.
-The higher the number of ideal health factors, the lower the risk of chronic kidney disease.
-There were 2,743 cases of chronic kidney disease during an average of 22 years of follow up.
-The number of ideal Life’s Simple 7 health factors was significantly associated with chronic kidney disease even after accounting for age, sex, race, and a test to gauge kidney function, called glomerular filtration rate (GFR).
-The narrowing of arteries that underlies heart disease also damages the blood vessels in the kidneys, so that the nephrons – which filter waste out of blood – no longer get the oxygen and nutrients they need to work effectively. In addition, damaged kidneys are less able to produce a hormone needed to regulate blood pressure.
“The shared underlying processes leading to the development of cardiovascular and kidney disease suggests that Life’s Simple 7 might also be effective for kidney disease prevention,” Rebholz said.